The voltage-gated potassium channels and their relatives

Gary Yellen ()
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Gary Yellen: Harvard Medical School

Nature, 2002, vol. 419, issue 6902, 35-42

Abstract: Abstract The voltage-gated potassium channels are the prototypical members of a family of membrane signalling proteins. These protein-based machines have pores that pass millions of ions per second across the membrane with astonishing selectivity, and their gates snap open and shut in milliseconds as they sense changes in voltage or ligand concentration. The architectural modules and functional components of these sophisticated signalling molecules are becoming clear, but some important links remain to be elucidated.

Date: 2002
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DOI: 10.1038/nature00978

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