Unravelling the signal-transduction network in B lymphocytes

Gilberto R. Sambrano (), Grischa Chandy, Sangdun Choi, Dianne Decamp, Robert Hsueh, Keng-Mean Lin, Dennis Mock, Nancy O'Rourke, Tamara Roach, Hongjun Shu, Bob Sinkovits, Mary Verghese and Henry Bourne
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Gilberto R. Sambrano: University of California, San Francisco
Grischa Chandy: Stanford University School of Medicine
Sangdun Choi: 147-75, California Institute of Technology
Dianne Decamp: University of Texas Southwestern Medical Center
Robert Hsueh: University of Texas Southwestern Medical Center
Keng-Mean Lin: University of Texas Southwestern Medical Center
Dennis Mock: San Diego Supercomputer Center, University of California, San Diego
Nancy O'Rourke: Stanford University School of Medicine
Tamara Roach: San Francisco Veterans Administration Medical Center
Hongjun Shu: University of Texas Southwestern Medical Center
Bob Sinkovits: San Diego Supercomputer Center, University of California, San Diego
Mary Verghese: Stanford University School of Medicine
Henry Bourne: University of California, San Francisco

Nature, 2002, vol. 420, issue 6916, 708-710

Abstract: Abstract The Alliance for Cellular Signaling has chosen the mouse B lymphocyte as a model system to understand basic principles that govern cellular signalling. Progress to that end has focused initially on establishing a reproducible experimental cell system and characterizing essential signalling responses. Although unravelling this complex network will take years, findings revealed in the interim will prove immensely useful to the scientific community at large.

Date: 2002
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DOI: 10.1038/nature01305

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