Navigating the signalling network in mouse cardiac myocytes

Gilberto R. Sambrano (), Iain Fraser, Heping Han, Yan Ni, Tim O'Connell, Zhen Yan and James T. Stull
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Gilberto R. Sambrano: University of California, San Francisco
Iain Fraser: 147-75, California Institute of Technology
Heping Han: University of Texas Southwestern Medical Center
Yan Ni: University of Texas Southwestern Medical Center
Tim O'Connell: San Francisco Veterans Administration Medical Center
Zhen Yan: University of Texas Southwestern Medical Center
James T. Stull: University of Texas Southwestern Medical Center

Nature, 2002, vol. 420, issue 6916, 712-714

Abstract: Abstract Cardiac myocytes have a complex network of signals that regulates their essential role in the rhythmic pumping of the heart. This network is an appealing model system in which to study the basic principles underlying cellular signalling mechanisms. Progress in this effort has come through the establishment of standardized myocyte isolation and culture procedures and characterization of important signalling responses.

Date: 2002
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DOI: 10.1038/nature01306

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