Carbon nanotubes with DNA recognition

Keith A. Williams (), Peter T. M. Veenhuizen, Beatriz G. de la Torre, Ramon Eritja and Cees Dekker
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Keith A. Williams: Delft University of Technology
Peter T. M. Veenhuizen: Delft University of Technology
Beatriz G. de la Torre: Instituto de Biologia Molecular Barcelona, Consejo Superior de Investigaciones Cientificas
Ramon Eritja: Instituto de Biologia Molecular Barcelona, Consejo Superior de Investigaciones Cientificas
Cees Dekker: Delft University of Technology

Nature, 2002, vol. 420, issue 6917, 761-761

Abstract: Abstract Since the discovery of their one-dimensional electronic band structure1, the leading candidate that has emerged for nanodevice applications is single-walled carbon nanotubes (SWNTs) . Here we unite their unique properties with the specific molecular-recognition features of DNA by coupling SWNTs to peptide nucleic acid (PNA, an uncharged DNA analogue2) and hybridizing these macromolecular wires with complementary DNA. Our findings provide a new, versatile means of incorporating SWNTs into larger electronic devices by recognition-based assembly, and of using SWNTs as probes in biological systems by sequence-specific attachment.

Date: 2002
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DOI: 10.1038/420761a

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