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The digital code of DNA

Leroy Hood () and David Galas ()
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Leroy Hood: Institute for Systems Biology
David Galas: Keck Graduate Institute of Applied Sciences

Nature, 2003, vol. 421, issue 6921, 444-448

Abstract: Abstract The discovery of the structure of DNA transformed biology profoundly, catalysing the sequencing of the human genome and engendering a new view of biology as an information science. Two features of DNA structure account for much of its remarkable impact on science: its digital nature and its complementarity, whereby one strand of the helix binds perfectly with its partner. DNA has two types of digital information — the genes that encode proteins, which are the molecular machines of life, and the gene regulatory networks that specify the behaviour of the genes.

Date: 2003
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DOI: 10.1038/nature01410

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