Inferences, questions and possibilities in Toll-like receptor signalling

Bruce Beutler ()
Additional contact information
Bruce Beutler: The Scripps Research Institute

Nature, 2004, vol. 430, issue 6996, 257-263

Abstract: Abstract The Toll-like receptors (TLRs) are the key proteins that allow mammals — whether immunologically naive or experienced — to detect microbes. They lie at the core of our inherited resistance to disease, initiating most of the phenomena that occur in the course of infection. Quasi-infectious stimuli that have been used for decades to study inflammatory mechanisms can activate the TLR family of proteins. And it now seems that many inflammatory processes, both sterile and infectious, may depend on TLR signalling. We are in a good position to apply our understanding of TLR signalling to a range of challenges in immunology and medicine.

Date: 2004
References: Add references at CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.nature.com/articles/nature02761 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:430:y:2004:i:6996:d:10.1038_nature02761

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature02761

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().