Translating cell biology in vitro to immunity in vivo

Marianne Boes () and Hidde L. Ploegh ()
Additional contact information
Marianne Boes: Harvard Medical School
Hidde L. Ploegh: Harvard Medical School

Nature, 2004, vol. 430, issue 6996, 264-271

Abstract: Abstract The elimination of pathogens and pathogen-infected cells initially rests on the rapid deployment of innate immune defences. Should these defences fail, it is the lymphocytes — T cells and B cells — with their antigen-specific receptors that must rise to the task of providing adaptive immunity. Technological advances are now allowing immunologists to correlate data obtained in vitro with in vivo functions. A better understanding of T-cell activation in vivo could lead to more effective strategies for the treatment and prevention of infectious and autoimmmune diseases.

Date: 2004
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/nature02762 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:430:y:2004:i:6996:d:10.1038_nature02762

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature02762

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().