Lessons from natural molecules

Jon Clardy () and Christopher Walsh
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Jon Clardy: Harvard Medical School
Christopher Walsh: Harvard Medical School

Nature, 2004, vol. 432, issue 7019, 829-837

Abstract: Abstract Natural products have inspired chemists and physicians for millennia. Their rich structural diversity and complexity has prompted synthetic chemists to produce them in the laboratory, often with therapeutic applications in mind, and many drugs used today are natural products or natural-product derivatives. Recent years have seen considerable advances in our understanding of natural-product biosynthesis. Coupled with improvements in approaches for natural-product isolation, characterization and synthesis, these could be opening the door to a new era in the investigation of natural products in academia and industry.

Date: 2004
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DOI: 10.1038/nature03194

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