Regulation of axon growth in vivo by activity-based competition

Jackie Yuanyuan Hua (), Matthew C. Smear, Herwig Baier and Stephen J. Smith
Additional contact information
Jackie Yuanyuan Hua: Stanford University
Matthew C. Smear: University of California, San Francisco
Herwig Baier: University of California, San Francisco
Stephen J. Smith: Stanford University

Nature, 2005, vol. 434, issue 7036, 1022-1026

Abstract: Same-sex mating: cryptic couples The sex life of the pathogen Cryptococcus neoformans is rather mysterious. This fungus, which is a common cause of illness in AIDS patients, has two mating types, α and a, yet the vast majority of clinical isolates are of the α type. Sexual congress between the two mating types is necessarily rare, but now the fruiting process, involving α cells only and previously considered strictly mitotic and asexual, is revealed as an unusual form of the sexual cycle. As the α mating type has been linked to virulence, these studies also have implications for the mechanism of pathogenicity.

Date: 2005
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DOI: 10.1038/nature03409

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