Sterol sensor comes up for air
Renee M. Garza and
Randolph Y. Hampton ()
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Renee M. Garza: Section of Cell and Developmental Biology, University of California at San Diego
Randolph Y. Hampton: Section of Cell and Developmental Biology, University of California at San Diego
Nature, 2005, vol. 435, issue 7038, 37-38
Abstract:
In one example of a feedback mechanism in mammals, cells switch cholesterol synthesis on or off depending on the availability of sterol. A rewired version of this pathway in yeast acts instead as an oxygen sensor.
Date: 2005
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DOI: 10.1038/435037a
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