Kinase-regulated quantal assemblies and kiss-and-run recycling of caveolae

Lucas Pelkmans () and Marino Zerial
Additional contact information
Lucas Pelkmans: Max Planck Institute for Molecular Cell Biology and Genetics
Marino Zerial: Max Planck Institute for Molecular Cell Biology and Genetics

Nature, 2005, vol. 436, issue 7047, 128-133

Abstract: Kinome truths A genome-wide analysis of the human kinome — the sum total of protein, lipid and carbohydrate kinases — shows that the cell's signalling functions are intimately linked to endocytosis, the process by which material is imported into the cell inside a membrane vesicle. Many of the kinases involved in endocytosis are known to function in mitogenic signalling, stimulating cell division and lymphocyte transformation: this adds to growing evidence that endocytic transport and signal transduction are integrated processes. An accompanying manuscript looks at the role of some of the kinases identified in the kinome screen, revealing novel dynamic properties of caveola/raft-mediated endocytosis that are distinct from the current picture of membrane transport.

Date: 2005
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/nature03866 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:436:y:2005:i:7047:d:10.1038_nature03866

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature03866

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().