Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system
Shiladitya Sengupta,
David Eavarone,
Ishan Capila,
Ganlin Zhao,
Nicki Watson,
Tanyel Kiziltepe and
Ram Sasisekharan ()
Additional contact information
Shiladitya Sengupta: Biological Engineering Division
David Eavarone: Biological Engineering Division
Ishan Capila: Biological Engineering Division
Ganlin Zhao: Biological Engineering Division
Nicki Watson: Whitehead Institute for Biomedical Research
Tanyel Kiziltepe: Massachusetts Institute of Technology
Ram Sasisekharan: Biological Engineering Division
Nature, 2005, vol. 436, issue 7050, 568-572
Abstract:
Balloon debate Anti-angiogenesis therapy stops tumour growth by cutting the blood supply, but its clinical use has been problematic. A new ‘balloon-within-a-balloon’ nanocell system that delivers anti-angiogenesis and conventional chemotherapeutic agents sequentially may be the answer.
Date: 2005
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DOI: 10.1038/nature03794
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