Interference with AI-2-mediated bacterial cell–cell communication

Karina B. Xavier and Bonnie L. Bassler ()
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Karina B. Xavier: Princeton University
Bonnie L. Bassler: Princeton University

Nature, 2005, vol. 437, issue 7059, 750-753

Abstract: Calling all bacteria In a process called quorum sensing, bacteria communicate with each other using chemical signal molecules. This allows bacterial populations to synchronize their behaviour, and to act in some respects as multicellular organisms. One chemical communication molecule, called autoinducer-2 (AI-2), is a universal molecule that bacteria use to communicate between species. Some species of bacteria are now shown to interfere with AI-2-directed communication. This may give them an advantage in mixed-species communities, in the human gut microflora for instance.

Date: 2005
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DOI: 10.1038/nature03960

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