Mapping determinants of human gene expression by regional and genome-wide association

Vivian G. Cheung (), Richard S. Spielman (), Kathryn G. Ewens, Teresa M. Weber, Michael Morley and Joshua T. Burdick
Additional contact information
Vivian G. Cheung: University of Pennsylvania
Richard S. Spielman: University of Pennsylvania
Kathryn G. Ewens: University of Pennsylvania
Teresa M. Weber: University of Pennsylvania
Michael Morley: The Children's Hospital of Philadelphia
Joshua T. Burdick: The Children's Hospital of Philadelphia

Nature, 2005, vol. 437, issue 7063, 1365-1369

Abstract: Self expression Even when two humans have the same genes, the levels at which those genes are expressed can contribute greatly to variation between individuals. Based on HapMap Project data, Cheung et al. use genetic association to map the parts of each gene that control levels of expression. The data also provide a detailed comparison of the techniques of genetic linkage and association, both of which are used to look for genetic determinants of human disease.

Date: 2005
References: Add references at CitEc
Citations: View citations in EconPapers (14)

Downloads: (external link)
https://www.nature.com/articles/nature04244 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:437:y:2005:i:7063:d:10.1038_nature04244

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature04244

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().