Pet project

Stephen J. O'Brien
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Stephen J. O'Brien: the Laboratory of Genomic Diversity, National Cancer Institute

Nature, 2005, vol. 438, issue 7069, 740-740

Abstract: The Dog Genome The genome of the domestic dog is arguably the most interesting of the 5,500 species of mammals on Earth, genetically speaking. The remarkable diversity between breeds, created by a brief period of intensive human-driven selection for behavioural and physical traits, means that its sequence contains critical clues to understanding genome evolution and organization, and predisposition to disease. In this issue, Lindblad-Toh et al. publish the high-quality draft sequence of the dog genome – that of female boxer Tasha – and outline some of the genetic differences between breeds. Comparative analysis with humans and rodents provides a general perspective on gene and genome evolution. And see Books and Arts for a review of the book of the genome. (Cover art: Bang Wong, Broad Institute of MIT and Harvard. Photos: Alison Ruhe, University of California, Davis. Watson and Crick: A Barrington Brown/SPL). See also Genome Research

Date: 2005
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DOI: 10.1038/438740a

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