Lymphangiogenesis in development and human disease

Kari Alitalo (), Tuomas Tammela and Tatiana V. Petrova
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Kari Alitalo: Molecular/Cancer Biology Laboratory, Ludwig Institute for Cancer, Research
Tuomas Tammela: Molecular/Cancer Biology Laboratory, Ludwig Institute for Cancer, Research
Tatiana V. Petrova: Development and Differentiation Laboratory, Molecular/Cancer Biology Program, Biomedicum Helsinki, Haartman Institute and Helsinki University Central Hospital

Nature, 2005, vol. 438, issue 7070, 946-953

Abstract: Abstract The lymphatic vasculature forms a vessel network that drains interstitial fluid from tissues and returns it to the blood. Lymphatic vessels are also an essential part of the body's immune defence. They have an important role in the pathogenesis of several diseases, such as cancer, lymphoedema and various inflammatory conditions. Recent biological and technological developments in lymphatic vascular biology will lead to a better understanding and treatment of these diseases.

Date: 2005
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DOI: 10.1038/nature04480

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