SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope
Ghislain G. Cabal,
Auguste Genovesio,
Susana Rodriguez-Navarro,
Christophe Zimmer,
Olivier Gadal,
Annick Lesne,
Henri Buc,
Frank Feuerbach-Fournier,
Jean-Christophe Olivo-Marin (),
Eduard C. Hurt and
Ulf Nehrbass ()
Additional contact information
Ghislain G. Cabal: Unité de Biologie Cellulaire du Noyau
Auguste Genovesio: Unité d'Analyse d'Images Quantitative
Susana Rodriguez-Navarro: Biochemie-Zentrum der Universität Heidelberg (BZH)
Christophe Zimmer: Unité d'Analyse d'Images Quantitative
Olivier Gadal: Unité de Biologie Cellulaire du Noyau
Annick Lesne: Laboratoire de Physique Théorique de la Matière Condensée
Henri Buc: Institut Pasteur
Frank Feuerbach-Fournier: Unité de Biologie Cellulaire du Noyau
Jean-Christophe Olivo-Marin: Unité d'Analyse d'Images Quantitative
Eduard C. Hurt: Biochemie-Zentrum der Universität Heidelberg (BZH)
Ulf Nehrbass: Institut Pasteur Korea
Nature, 2006, vol. 441, issue 7094, 770-773
Abstract:
In the right place It is becoming clear that the position of genes within the nucleus can influence their expression, and two groups this week report examples of this in yeast. Cabal et al. find that activation of GAL genes confines them to the nuclear periphery. And Taddei et al. report that simply moving the HXK1 gene, by blocking or encouraging its association with the nuclear periphery, significantly alters gene expression.
Date: 2006
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DOI: 10.1038/nature04752
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