Social interactions among epithelial cells during tracheal branching morphogenesis

Amin S. Ghabrial and Mark A. Krasnow ()
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Amin S. Ghabrial: Stanford University School of Medicine
Mark A. Krasnow: Stanford University School of Medicine

Nature, 2006, vol. 441, issue 7094, 746-749

Abstract: Genetic mosaic analysis in Drosophila melanogaster shows that there are two classes of cells in the budding tracheal branches: those that migrate to the tip, and those that follow these lead cells and form a tube. The position of the cell results from competition within the population, with those expressing the highest level of FGF taking the lead positions at the tip, and the others forming the branch stalk.

Date: 2006
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DOI: 10.1038/nature04829

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