Potential of stem-cell-based therapies for heart disease
Deepak Srivastava () and
Kathryn N. Ivey
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Deepak Srivastava: University of California San Francisco
Kathryn N. Ivey: University of California San Francisco
Nature, 2006, vol. 441, issue 7097, 1097-1099
Abstract:
Abstract The use of stem cells to generate replacement cells for damaged heart muscle, valves, vessels and conduction cells holds great potential. Recent identification of multipotent progenitor cells in the heart and improved understanding of developmental processes relevant to pluripotent embryonic stem cells may facilitate the generation of specific types of cell that can be used to treat human heart disease. Secreted factors from circulating progenitor cells that localize to sites of damage may also be useful for tissue protection or neovascularization. The exciting discoveries in basic science will require rigorous testing in animal models to determine those most worthy of future clinical trials.
Date: 2006
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:441:y:2006:i:7097:d:10.1038_nature04961
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DOI: 10.1038/nature04961
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