Does prepatterning occur in the mouse egg?

Takashi Hiiragi (), Sophie Louvet-Vallée, Davor Solter and Bernard Maro
Additional contact information
Takashi Hiiragi: Max Planck Institute of Immunobiology
Sophie Louvet-Vallée: Laboratoire de Biologie Cellulaire du Développement, UMR 7622, CNRS, Université Pierre et Marie Curie
Davor Solter: Max Planck Institute of Immunobiology
Bernard Maro: Laboratoire de Biologie Cellulaire du Développement, UMR 7622, CNRS, Université Pierre et Marie Curie

Nature, 2006, vol. 442, issue 7099, E3-E4

Abstract: Abstract Arising from: B. Plusa et al. Nature 434, 391–395 (2005); Plusa et al. reply A recurring question in developmental biology has been whether localized determinants play any role in mammalian preimplantation development1. This is a controversial issue that brings back the idea of prepatterning2,3,4 and is explored further by Plusa et al.5, who claim it is the first cleavage of the mouse zygote that predicts the blastocyst axis, rather than the animal pole or sperm entry point, as previously suggested3. However, other evidence indicates that the blasotcyst axis is not predetermined and there is no prepatterning in the mouse egg6,7,8,9,10,11,12. Here we investigate the origin of these different views and conclude that they arise from differences in the data themselves and in their interpretation.

Date: 2006
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/nature04907 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:442:y:2006:i:7099:d:10.1038_nature04907

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature04907

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().