Mesodermal Wnt2b signalling positively regulates liver specification

Elke A. Ober (), Heather Verkade, Holly A. Field and Didier Y. R. Stainier ()
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Elke A. Ober: University of California
Heather Verkade: University of California
Holly A. Field: University of California
Didier Y. R. Stainier: University of California

Nature, 2006, vol. 442, issue 7103, 688-691

Abstract: This paper describes the identification of the only single gene that is known to exclusively regulate liver specification, and shows that liver formation is regulated by inductive Wnt signals and crosstalk between the endoderm and mesoderm along the gut tube.

Date: 2006
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DOI: 10.1038/nature04888

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