Signal sequence directs localized secretion of bacterial surface proteins

Fredric Carlsson, Margaretha Stålhammar-Carlemalm, Klas Flärdh, Charlotta Sandin, Eric Carlemalm and Gunnar Lindahl ()
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Fredric Carlsson: Department of Laboratory Medicine
Margaretha Stålhammar-Carlemalm: Department of Laboratory Medicine
Klas Flärdh: Department of Cell and Organism Biology
Charlotta Sandin: Department of Laboratory Medicine
Eric Carlemalm: Lund University
Gunnar Lindahl: Department of Laboratory Medicine

Nature, 2006, vol. 442, issue 7105, 943-946

Abstract: To ensure proper identification by the secretion machinery, surface and extracellular proteins contain specific signal sequences. This paper reveals that the information contained in these short tags can also be used to target proteins to specific locations within the bacterial cell.

Date: 2006
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DOI: 10.1038/nature05021

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