A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula

Kevin M. Vogeli, Suk-Won Jin, Gail R. Martin and Didier Y. R. Stainier ()
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Kevin M. Vogeli: Department of Biochemistry and Biophysics
Suk-Won Jin: Department of Biochemistry and Biophysics
Gail R. Martin: Department of Anatomy
Didier Y. R. Stainier: Department of Biochemistry and Biophysics

Nature, 2006, vol. 443, issue 7109, 337-339

Abstract: Haemangioblast at last The haemangioblast is a biopotential precursor of both blood and endothelial cells that has been hypothesized to exist for almost 100 years, but for which formal proof has been lacking. Vogeli et al. now provide in vivo evidence for its existence. High-resolution, single cell lineage studies of zebrafish embryos show that the haemangioblast is present in the early fish embryo, and also reveal new information about its structure and function.

Date: 2006
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DOI: 10.1038/nature05045

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