Enzyme target to latch on to

Malcolm A. Leissring () and Dennis J. Selkoe ()
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Malcolm A. Leissring: Scripps Florida, The Scripps Research Institute
Dennis J. Selkoe: Center for Neurologic Diseases, Brigham & Women's Hospital, Harvard Medical School

Nature, 2006, vol. 443, issue 7113, 761-762

Abstract: Insulin-degrading enzyme is implicated in diabetes and Alzheimer's disease, but few molecular tools exist that can probe its function. A study now reveals its unusual structure and may lead to an expanded toolbox.

Date: 2006
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DOI: 10.1038/nature05210

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