Dangerous liaisons on neurons

Giampietro Schiavo ()
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Giampietro Schiavo: Molecular Neuropathobiology Laboratory, Cancer Research UK, London Research Institute

Nature, 2006, vol. 444, issue 7122, 1019-1020

Abstract: Crystal structures show that botulinum toxins bind simultaneously to two sites on neurons. This dual interaction allows them to use a Trojan-horse strategy to enter nerve terminals, with deadly effect.

Date: 2006
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DOI: 10.1038/nature05410

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