Mechanisms of sensory transduction in the skin

Ellen A. Lumpkin () and Michael J. Caterina ()
Additional contact information
Ellen A. Lumpkin: Molecular Physiology & Biophysics and Molecular & Human Genetics, Baylor College of Medicine, One Baylor Plaza
Michael J. Caterina: and the Center for Sensory Biology, The Johns Hopkins School of Medicine

Nature, 2007, vol. 445, issue 7130, 858-865

Abstract: Abstract Sensory neurons innervating the skin encode the familiar sensations of temperature, touch and pain. An explosion of progress has revealed unanticipated cellular and molecular complexity in these senses. It is now clear that perception of a single stimulus, such as heat, requires several transduction mechanisms. Conversely, a given protein may contribute to multiple senses, such as heat and touch. Recent studies have also led to the surprising insight that skin cells might transduce temperature and touch. To break the code underlying somatosensation, we must therefore understand how the skin's sensory functions are divided among signalling molecules and cell types.

Date: 2007
References: Add references at CitEc
Citations: View citations in EconPapers (6)

Downloads: (external link)
https://www.nature.com/articles/nature05662 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:445:y:2007:i:7130:d:10.1038_nature05662

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature05662

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().