A mirror-symmetric cell division that orchestrates neuroepithelial morphogenesis

Marcel Tawk, Claudio Araya, Dave A. Lyons, Alexander M. Reugels, Gemma C. Girdler, Philippa R. Bayley, David R. Hyde, Masazumi Tada and Jonathan D. W. Clarke ()
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Marcel Tawk: Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK
Claudio Araya: Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK
Dave A. Lyons: Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK
Alexander M. Reugels: Institut für Entwicklungsbiologie, Universität zu Köln, 50923 Köln, Germany
Gemma C. Girdler: Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK
Philippa R. Bayley: Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK
David R. Hyde: University of Notre Dame, Notre Dame, Indiana 46556, USA
Masazumi Tada: Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK
Jonathan D. W. Clarke: Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK

Nature, 2007, vol. 446, issue 7137, 797-800

Abstract: In the developing neural tube of the zebrafish, a newly discovered kind of cell division occurs that produces two daughter cells with mirror symmetry. Cells are polarized in mirror symmetry on either side of the neural midline, and Pard3, a protein known to be involved in polarized cell divisions, is deposited within the cleavage furrow of the midline.

Date: 2007
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DOI: 10.1038/nature05722

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