A positive feedback mechanism governs the polarity and motion of motile cilia
Brian Mitchell,
Richard Jacobs,
Julie Li,
Shu Chien and
Chris Kintner ()
Additional contact information
Brian Mitchell: The Salk Institute for Biological Studies, La Jolla, California 92186, USA
Richard Jacobs: The Salk Institute for Biological Studies, La Jolla, California 92186, USA
Julie Li: University of California San Diego, La Jolla, California 92093, USA
Shu Chien: University of California San Diego, La Jolla, California 92093, USA
Chris Kintner: The Salk Institute for Biological Studies, La Jolla, California 92186, USA
Nature, 2007, vol. 447, issue 7140, 97-101
Abstract:
On cells with motile cilia, cilia not only generate flow along a specific axis, but are involved in sensing and responding to that flow in a way that influences cell polarity. This model suggests a new paradigm for how polarity can be generated in a developing tissue, which will be of general interest to all developmental biologists.
Date: 2007
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:447:y:2007:i:7140:d:10.1038_nature05771
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DOI: 10.1038/nature05771
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