The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks

Michael Kruhlak, Elizabeth E. Crouch, Marika Orlov, Carolina Montaño, Stanislaw A. Gorski, André Nussenzweig, Tom Misteli, Robert D. Phair and Rafael Casellas ()
Additional contact information
Michael Kruhlak: Experimental Immunology, NCI
Elizabeth E. Crouch: Genomic Integrity and Immunity, NIAMS
Marika Orlov: Genomic Integrity and Immunity, NIAMS
Carolina Montaño: Genomic Integrity and Immunity, NIAMS
Stanislaw A. Gorski: Biology of Genomes, NCI, National Institutes of Health, Bethesda, Maryland 20892, USA
André Nussenzweig: Experimental Immunology, NCI
Tom Misteli: Biology of Genomes, NCI, National Institutes of Health, Bethesda, Maryland 20892, USA
Robert D. Phair: Integrative Bioinformatics, Los Altos, California 94024, USA
Rafael Casellas: Genomic Integrity and Immunity, NIAMS

Nature, 2007, vol. 447, issue 7145, 730-734

Abstract: DNA damage leads to transient repression of ribosomal gene transcription by RNA polymerase I in a pathway mediated by ATM kinase activity and the DNA repair factors Nbs1 and MDC1

Date: 2007
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/nature05842 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:447:y:2007:i:7145:d:10.1038_nature05842

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature05842

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().