Crystal structure of the MgtE Mg2+ transporter

Motoyuki Hattori, Yoshiki Tanaka, Shuya Fukai, Ryuichiro Ishitani and Osamu Nureki ()
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Motoyuki Hattori: Graduate School of Bioscience and Biotechnology
Yoshiki Tanaka: Graduate School of Bioscience and Biotechnology
Shuya Fukai: Center for Biological Resources and Informatics, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama-shi, Kanagawa 226-8501, Japan
Ryuichiro Ishitani: Graduate School of Bioscience and Biotechnology
Osamu Nureki: Graduate School of Bioscience and Biotechnology

Nature, 2007, vol. 448, issue 7157, 1072-1075

Abstract: The crystal structure of a member of the MgtE family of Mg2+ transporters at 3.5Å resolution, and the structure of just the cytoplasmic domain in the presence and absence of Mg2+ is described. An elegant gating mechanism involving negative feedback by Mg2+ is also proposed.

Date: 2007
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DOI: 10.1038/nature06093

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