The remarkable metal-catalysed olefin metathesis reaction

Amir H. Hoveyda () and Adil R. Zhugralin
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Amir H. Hoveyda: Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, USA
Adil R. Zhugralin: Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, USA

Nature, 2007, vol. 450, issue 7167, 243-251

Abstract: Organometallic chemistry Catalytic olefin metathesis is a powerful chemical transformation that can convert simple double-bond containing compounds into more complex chemical entities. For this reason, it has become an important tool for the chemical synthesis of various natural products, drugs and polymers. In a Review Article, Amir Hoveyda and Adil Zhugralin discuss the catalysts that make this Nobel-prize winning reaction possible, illustrate how metathesis can be used to synthesize complex natural products, and highlight several key issues that still need to be addressed if the potential of this catalytic process is to be fully realized.

Date: 2007
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DOI: 10.1038/nature06351

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