Paradox of a tumour repressor

David W. Threadgill
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David W. Threadgill: University of North Carolina at Chapel Hill, North Carolina 27599, USA. dwt@med.unc.edu

Nature, 2008, vol. 451, issue 7174, 21-22

Abstract: Having three copies of chromosome 21 reduces the incidence of solid tumours in people with Down's syndrome. Studies in mice provide clues to why, and highlight a complex gene–function relationship.

Date: 2008
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DOI: 10.1038/451021a

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