Distinct roles of the FliI ATPase and proton motive force in bacterial flagellar protein export
Tohru Minamino and
Keiichi Namba ()
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Tohru Minamino: Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan
Keiichi Namba: Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan
Nature, 2008, vol. 451, issue 7177, 485-488
Abstract:
Alternative energy Bacterial flagella contain a secretion apparatus related to the type III secretion system used by many pathogens to transfer effector proteins into host cells. It is generally assumed that the ATPase FliI provides energy for transport, but two reports argue against this view. Both groups find that flagellar secretion occurs even in the absence of the ATPase, and that the energy required derives from the proton motive force.
Date: 2008
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DOI: 10.1038/nature06449
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