Energy source of flagellar type III secretion

Koushik Paul, Marc Erhardt, Takanori Hirano, David F. Blair () and Kelly T. Hughes ()
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Koushik Paul: University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112, USA
Marc Erhardt: University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112, USA
Takanori Hirano: University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112, USA
David F. Blair: University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112, USA
Kelly T. Hughes: University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112, USA

Nature, 2008, vol. 451, issue 7177, 489-492

Abstract: Alternative energy Bacterial flagella contain a secretion apparatus related to the type III secretion system used by many pathogens to transfer effector proteins into host cells. It is generally assumed that the ATPase FliI provides energy for transport, but two reports argue against this view. Both groups find that flagellar secretion occurs even in the absence of the ATPase, and that the energy required derives from the proton motive force.

Date: 2008
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DOI: 10.1038/nature06497

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