Cell cycle control of centromeric repeat transcription and heterochromatin assembly

Ee Sin Chen, Ke Zhang, Estelle Nicolas, Hugh P. Cam, Martin Zofall and Shiv I. S. Grewal ()
Additional contact information
Ee Sin Chen: Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Ke Zhang: Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Estelle Nicolas: Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Hugh P. Cam: Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Martin Zofall: Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Shiv I. S. Grewal: Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA

Nature, 2008, vol. 451, issue 7179, 734-737

Abstract: RNA polymerase II transcribes heterochromatic repeat sequences preferentially during S-phase of the cell cycle, a timing that is enforced by heterochromatin restricting RNAPII access. Chromatin modifying enzymes and RNAi complexes associated with RNAPII then assemble silenced chromatin which is maintained until the next S phase.

Date: 2008
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://www.nature.com/articles/nature06561 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:451:y:2008:i:7179:d:10.1038_nature06561

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature06561

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().