Formation and branch migration of Holliday junctions mediated by eukaryotic recombinases

Yasuto Murayama, Yumiko Kurokawa, Kouta Mayanagi and Hiroshi Iwasaki ()
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Yasuto Murayama: International Graduate School of Arts and Sciences, Yokohama City University, 1-7-29, Suehirocho, Tsurumi, Yokohama, Kanagawa 230-0045, Japan
Yumiko Kurokawa: International Graduate School of Arts and Sciences, Yokohama City University, 1-7-29, Suehirocho, Tsurumi, Yokohama, Kanagawa 230-0045, Japan
Kouta Mayanagi: Nagahama Institute of Bio-Science and Technology, 1266, Tamura, Nagahama, Shiga 526-0829, Japan
Hiroshi Iwasaki: International Graduate School of Arts and Sciences, Yokohama City University, 1-7-29, Suehirocho, Tsurumi, Yokohama, Kanagawa 230-0045, Japan

Nature, 2008, vol. 451, issue 7181, 1018-1021

Abstract: Although the bacterial RecA protein has been previously described to facilitate reciprocal duplex DNA exchange, here the first eukaryotic proteins, yeast Rhp51 and human Rad51, are demonstrated to catalyse this process.

Date: 2008
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DOI: 10.1038/nature06609

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