A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs

David L. Mellman, Michael L. Gonzales, Chunhua Song, Christy A. Barlow, Ping Wang, Christina Kendziorski and Richard A. Anderson ()
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David L. Mellman: Program in Molecular and Cellular Pharmacology,
Michael L. Gonzales: Program in Molecular and Cellular Pharmacology,
Chunhua Song: and
Christy A. Barlow: and
Ping Wang: University of Wisconsin Medical School, University of Wisconsin-Madison, 1300 University Avenue, Madison, Wisconsin 53706, USA
Christina Kendziorski: University of Wisconsin Medical School, University of Wisconsin-Madison, 1300 University Avenue, Madison, Wisconsin 53706, USA
Richard A. Anderson: Program in Molecular and Cellular Pharmacology,

Nature, 2008, vol. 451, issue 7181, 1013-1017

Abstract: A new polyadenylation polymerase, called Star-PAP, is identified, the activity of which is regulated by nuclear phosphoinositides generated by the kinase PIPKIα.

Date: 2008
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DOI: 10.1038/nature06666

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