A genetic framework for improving arrhythmia therapy

Björn C. Knollmann and Dan M. Roden
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Björn C. Knollmann: Vanderbilt University School of Medicine
Dan M. Roden: Vanderbilt University School of Medicine

Nature, 2008, vol. 451, issue 7181, 929-936

Abstract: Abstract Abnormalities in heart rhythm continue to cause high rates of illness and death. Better treatment could be provided by solving two main challenges: the early identification of patients who are at risk, and the characterization of molecular pathways that culminate in arrhythmias. By analysing mechanisms that increase susceptibility to arrhythmia in individuals with genetic syndromes, it might be possible to improve current therapies and to develop new ways to treat and prevent common arrhythmias.

Date: 2008
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DOI: 10.1038/nature06799

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