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Crossing over to drug resistance

David M. Livingston and Daniel P. Silver
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David M. Livingston: David M. Livingston and Daniel P. Silver are at the Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, Massachusetts 02115, USA. david_livingston@dfci.harvard.edu daniel_silver@dfci.harvard.edu
Daniel P. Silver: David M. Livingston and Daniel P. Silver are at the Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, Massachusetts 02115, USA. david_livingston@dfci.harvard.edu daniel_silver@dfci.harvard.edu

Nature, 2008, vol. 451, issue 7182, 1066-1067

Abstract: Certain cancers stem from mutations that prevent a cell from repairing its damaged DNA efficiently. But antitumour chemotherapy that exploits that repair defect can in turn be nullified by counter-mutation.

Date: 2008
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DOI: 10.1038/4511066a

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