Genetic basis of fitness differences in natural populations

Hans Ellegren () and Ben C. Sheldon ()
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Hans Ellegren: Evolutionary Biology Centre, Uppsala University, Norbyvägen 18D, SE-752 36 Uppsala, Sweden
Ben C. Sheldon: Edward Grey Institute, University of Oxford, South Parks Road, Oxford OX1 3PS, UK

Nature, 2008, vol. 452, issue 7184, 169-175

Abstract: Survival fit for a genome In their Review Article on the genetic basis of fitness, Hans Ellegren and Ben Sheldon argue that the fields of population biology and genomics are converging to a point where it will soon be possible to make major advances in our understanding of evolution in natural populations. Concentrating on animals — though similar work is being done with plants — they explain how genomic approaches can establish genotype–phenotype relationships in natural populations, giving insight into the genetic architecture of quantitative variation and the genetic substrate of natural selection.

Date: 2008
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DOI: 10.1038/nature06737

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