Preserving cell shape under environmental stress

Boaz Cook, Robert W. Hardy, William B. McConnaughey and Charles S. Zuker ()
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Boaz Cook: University of California at San Diego, La Jolla, California 92093-0649, USA
Robert W. Hardy: University of California at San Diego, La Jolla, California 92093-0649, USA
William B. McConnaughey: Washington University School of Medicine, St Louis, Missouri 63110, USA
Charles S. Zuker: University of California at San Diego, La Jolla, California 92093-0649, USA

Nature, 2008, vol. 452, issue 7185, 361-364

Abstract: An investigation into how poikilothermic organisms are able to maintain highly effective mechanical responses finds that a protein called Spam forms an extracellular shield that guards mechanosensory neurons from environmental insult. Spam also enables cells to resist physically and chemically induced deformation.

Date: 2008
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DOI: 10.1038/nature06603

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