Memory CD4 T cells emerge from effector T-cell progenitors

Laurie E. Harrington, Karen M. Janowski, James R. Oliver, Allan J. Zajac and Casey T. Weaver ()
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Laurie E. Harrington: and
Karen M. Janowski: and
James R. Oliver: and
Allan J. Zajac: University of Alabama at Birmingham, 845 19th Street South, Birmingham, Alabama 35294, USA
Casey T. Weaver: and

Nature, 2008, vol. 452, issue 7185, 356-360

Abstract: Naive CD4 and CD8 T cells give rise to effector and long-lived memory T cells after activation by antigen. This paper provides evidence that memory CD4 T cells, similar to their CD8 counterparts, differentiate in a linear fashion from effector cells rather than by an alternative differentiation pathway.

Date: 2008
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:452:y:2008:i:7185:d:10.1038_nature06672

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DOI: 10.1038/nature06672

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