Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons

Takako Makita, Henry M. Sucov, Cheryl E. Gariepy, Masashi Yanagisawa and David D. Ginty ()
Additional contact information
Takako Makita: Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Henry M. Sucov: Institute for Genetic Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
Cheryl E. Gariepy: University of Michigan, Ann Arbor, Michigan 48109, USA
Masashi Yanagisawa: Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA
David D. Ginty: Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA

Nature, 2008, vol. 452, issue 7188, 759-763

Abstract: This paper implicates vascular-derived endothelins in axonal growth and guidance. It is shown that the origin of smooth muscle cells surrounding the internal and external carotids is different and finds that they preferentially express components of the endothelin ligand-receptor system. The endothelin family member ET3 directs axon extension of a subset of sympathetic neurons to the external carotid artery.

Date: 2008
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/nature06859 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:452:y:2008:i:7188:d:10.1038_nature06859

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature06859

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().