Retinotopic order in the absence of axon competition

Nathan J. Gosse, Linda M. Nevin and Herwig Baier ()
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Nathan J. Gosse: Program in Developmental Biology, and,
Linda M. Nevin: Program in Neuroscience, University of California, San Francisco, 1550 Fourth Street, San Francisco, California 94158-2324, USA
Herwig Baier: Program in Developmental Biology, and,

Nature, 2008, vol. 452, issue 7189, 892-895

Abstract: Use of transplantation to create mosaic zebrafish in which only one retinal ganglion cell develops in the eye enables the projection of this axon that innervates the tectum to be observed. It is found that these axons still navigate to their topographically correct target. The experiment rules out competition as essential for topographic specificity in the zebrafish.

Date: 2008
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DOI: 10.1038/nature06816

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