Life without RNase P
Lennart Randau,
Imke Schröder and
Dieter Söll ()
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Lennart Randau: Department of Molecular Biophysics and Biochemistry,
Imke Schröder: Immunology, and Molecular Genetics, University of California, Los Angeles, California 90095, USA
Dieter Söll: Department of Molecular Biophysics and Biochemistry,
Nature, 2008, vol. 453, issue 7191, 120-123
Abstract:
Proving the rule Transfer RNAs are first synthesized as longer forms which are then reprocessed. RNase P is the enzyme that clips off excess RNA to give the mature 5' end, and it is found universally. Except, that is, in Nanoarchaeum equitans. Randau et al. have now uncovered the secret of this novel microbe's 'life without RNaseP'. Rearrangements in the promoters of this archaeon's tRNA genes generate ready-to-go 'leaderless' tRNAs.
Date: 2008
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:453:y:2008:i:7191:d:10.1038_nature06833
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DOI: 10.1038/nature06833
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