An HIV secret uncovered

Eddy Arnold and Stefan G. Sarafianos
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Eddy Arnold: Eddy Arnold is at the Center for Advanced Biotechnology and Medicine, Rutgers University, 679 Hoes Lane, Piscataway, New Jersey 08854, USA. arnold@cabm.rutgers.edu
Stefan G. Sarafianos: Stefan G. Sarafianos is at the Christopher Bond Life Sciences Center, School of Medicine, University of Missouri, 1201 Rollins Street, Columbia, Missouri 65211, USA. sarafianoss@missouri.edu

Nature, 2008, vol. 453, issue 7192, 169-170

Abstract: With two catalytic activities and many substrates, how does HIV's reverse transcriptase enzyme know what to do to which substrate? Zooming in on the enzyme's molecular interactions provides tantalizing clues.

Date: 2008
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DOI: 10.1038/453169b

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