Regenerative medicine and human models of human disease

Kenneth R. Chien
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Kenneth R. Chien: Cardiovascular Research Center, Massachusetts General Hospital, Simches Research Center

Nature, 2008, vol. 453, issue 7193, 302-305

Abstract: Abstract Recent advances in stem-cell technology are now allowing the mechanisms of human disease to be studied in human cells. A new era for regenerative medicine is arising from such disease models, extending beyond early cell-based therapies and towards evaluating genetic variation in humans and identifying the molecular pathways that lead to disease, as well as targets for therapy.

Date: 2008
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DOI: 10.1038/nature07037

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