Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells

Yoshinori Kawamura, Kuniaki Saito, Taishin Kin, Yukiteru Ono, Kiyoshi Asai, Takafumi Sunohara, Tomoko N. Okada, Mikiko C. Siomi () and Haruhiko Siomi ()
Additional contact information
Yoshinori Kawamura: Institute for Genome Research, University of Tokushima
Kuniaki Saito: Institute for Genome Research, University of Tokushima
Taishin Kin: Computational Biology Research Center, Advanced Industrial Science and Technology
Yukiteru Ono: Information and Mathematical Science Laboratory, Inc.
Kiyoshi Asai: Computational Biology Research Center, Advanced Industrial Science and Technology
Takafumi Sunohara: Institute for Genome Research, University of Tokushima
Tomoko N. Okada: Institute for Genome Research, University of Tokushima
Mikiko C. Siomi: Institute for Genome Research, University of Tokushima
Haruhiko Siomi: Institute for Genome Research, University of Tokushima

Nature, 2008, vol. 453, issue 7196, 793-797

Abstract: Endo-siRNAs in Drosophila Transposable elements have recently been shown to be active in somatic as well as germline cells. Recently, a class of small RNAs, piRNAs, was shown to be expressed from retrotransposons in germline cells and to mediate their transcriptional silencing. In this study, Kawamura et al. identify another class of small RNAs, endogenous siRNAs (endo-siRNAs), many of which are expressed from (and repress) retrotransposons, but in somatic cells. Interestingly, endo-siRNAs and piRNAs interact with different subfamilies of Argonaute proteins involved in RNA inhibition.

Date: 2008
References: Add references at CitEc
Citations: View citations in EconPapers (3)

Downloads: (external link)
https://www.nature.com/articles/nature06938 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:453:y:2008:i:7196:d:10.1038_nature06938

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature06938

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().