Molecular cloaking devices

Thomas Kodadek
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Thomas Kodadek: University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9185, USA. e-mail: thomas.kodadek@utsouthwestern.edu

Nature, 2008, vol. 453, issue 7197, 861-862

Abstract: Protease enzymes cut other proteins into pieces, but some can be blocked by inhibitors. One such inhibitor binds to the substrate rather than the enzyme, suggesting a new tactic for drug discovery.

Date: 2008
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DOI: 10.1038/453861a

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