Modelling collagen diseases

Barbara Brodsky and Jean Baum
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Barbara Brodsky: University of Medicine and Dentistry of New Jersey — Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA. brodsky@umdnj.edu
Jean Baum: BioMaPs Institute, Rutgers University, Piscataway, New Jersey 08854, USA. jean.baum@rutgers.edu

Nature, 2008, vol. 453, issue 7198, 998-999

Abstract: Mutations in collagen lead to hereditary disorders such as brittle-bone disease. Peptide models for aberrant collagens are beginning to clarify how these amino-acid replacements lead to clinical problems.

Date: 2008
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DOI: 10.1038/453998a

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